A Brief Overview of Macular Degeneration
Macular degeneration, often called AMD or ARMD (age-related macular degeneration), is the leading cause of vision loss and blindness in Americans aged 65 and older.
AMD is a degeneration of the macula, central part of the retina responsible for the sharp vision needed to read or drive.
It is estimated that 2 million americans had advanced age-related macular degeneration. That number is expected to rise to almost 3 million by 2020.
Macular degeneration is diagnosed as either dry (non-neovascular) or wet (neovascular). Neovascular refers to growth of new blood vessels in an area where they are not supposed to be.
The dry form is more common than the wet, with about 85-90 percent of AMD patients diagnosed with dry AMD. The wet form of the disease usually leads to more serious vision loss.
Dry AMD is an early stage of the disease and may result from the aging and thinning of the macula, depositing of pigment in the macula or a combination of the two processes.
Gradual central vision loss may occur with dry macular degeneration but is not nearly as severe as wet AMD symptoms.
No FDA-approved treatment or prevention has been available for dry macular degeneration. until now:
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Wet Macular Degeneration (neovascular). In about 10 percent of cases, dry AMD progresses to the more advanced and damaging form of the eye disease. With wet macular degeneration, new blood vessels grow (neovascularization) beneath the retina and leak blood and fluid. This leakage causes permanent damage to light-sensitive retinal cells, which die off and create blind spots in central vision.
We often detect early signs of macular degeneration before symptoms occur – usually accomplished through a retinal exam.
The American Academy of Ophthalmology notes that findings regarding AMD and risk factors have been contradictory, depending on the study. The only risk factors consistently found in studies to be associated with the eye disease are aging and smoking.
